"Lunch and Learn"
"We Help the Nation"
Contact: Noreen Morgan, Vice President
Lunch and Learn Meetings Really Work
Our congratulations go to Kentucky Federation of Chapters President Noreene Morgan whose recent "Lunch and Learn" meeting at the Cincinnati Federal Building was directly responsible for the creation of NARFE Chapter 2359 that is totally comprised of active Federal employees. Noreene and Marlene deserves a hearty round of applause for their wonderful efforts in recruiting new NARFE members.
Contact: Noreen Morgan, President
Contact: Marlene Bunten , NARFE
District IV Vice President
From: USA Today / October 26, 2010
Heavy smoking in midlife more
than doubles your odds of developing Alzheimer's disease, a Kaiser Permanente
study said Monday.
Researchers evaluated the records of 21,123 men and women, who, starting in midlife, were followed for an average of 23 years. Of 5,367 study participants diagnosed with dementia later in life, 2,367 were smokers, and 261 were heavy smokers (more than two packs a day). Compared with non-smokers, those who had smoked two packs of cigarettes a day increased their risk of developing Alzheimer's by more than 157% and had a 172% higher risk of developing vascular dementia — the second-most-common form of dementia after Alzheimer's. The research is published online in the Archives of Internal Medicine (see abstract below).
Though the study was observational, the authors have theories about what might be going on, Whitmer says. "People who smoke have increased inflammation, and we know inflammation also plays a role in Alzheimer's," she says.
Dementia experts say the new research is strong. "This study is particularly good because it separates out vascular dementia and Alzheimer's," says William Thies, the Alzheimer's Association's chief medical and scientific officer.
"The other novel aspect of it is that they've got a large enough sample to look at different ethnic groups, and it shows smoking's effect on dementia does not differ based on race," says Brenda Plassman, epidemiologist at Duke University Medical Center.
The bottom line: "If there's somebody out there who hasn't heard smoking's bad for you, they must live in a cave somewhere," Thies says. "This is another good reason not to smoke."
Heavy Smoking in Midlife and Long-term Risk of Alzheimer Disease and Vascular Dementia
Minna Rusanen, MD; Miia Kivipelto, MD, PhD; Charles P. Quesenberry Jr, PhD; Jufen Zhou, MS; Rachel A. Whitmer, PhD
Arch Intern Med. Published online October 25, 2010. doi:10.1001/archinternmed.2010.393
Background Smoking is a risk factor for several life-threatening diseases, but its long-term association with dementia is controversial and somewhat understudied. Our objective was to investigate the long-term association of amount of smoking in middle age on the risk of dementia, Alzheimer disease (AD), and vascular dementia (VaD) several decades later in a large, diverse population.
Methods We analyzed prospective data from a multiethnic population-based cohort of 21 123 members of a health care system who participated in a survey between 1978 and 1985. Diagnoses of dementia, AD, and VaD made in internal medicine, neurology, and neuropsychology were collected from January 1, 1994, to July 31, 2008. Multivariate Cox proportional hazards models were used to investigate the association between midlife smoking and risk of dementia, AD, and VaD.
Results A total of 5367 people (25.4%) were diagnosed as having dementia (including 1136 cases of AD and 416 cases of VaD) during a mean follow-up period of 23 years. Results were adjusted for age, sex, education, race, marital status, hypertension, hyperlipidemia, body mass index, diabetes, heart disease, stroke, and alcohol use. Compared with nonsmokers, those smoking more than 2 packs a day had an elevated risk of dementia (adjusted hazard ratio [HR], 2.14; 95% CI, 1.65-2.78), AD (adjusted HR, 2.57; 95% CI, 1.63-4.03), and VaD (adjusted HR, 2.72; 95% CI, 1.20-6.18).
Conclusions In this large cohort, heavy smoking in midlife was associated with a greater than 100% increase in risk of dementia, AD, and VaD more than 2 decades later. These results suggest that the brain is not immune to long-term consequences of heavy smoking.
Amy Jeffers, M.A., CPS
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